Analytical Validation of Relative Average Telomere Length Measurement in a Clinical Laboratory Environment
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چکیده
منابع مشابه
Effect of pre-analytic variables on the reproducibility of qPCR relative telomere length measurement
Telomeres, long nucleotide repeats and a protein complex at chromosome ends, shorten with each cell division and are susceptible to oxidative damage. Quantitative PCR (qPCR) is a widely-used technique to measure relative telomere length (RTL) in DNA samples but is challenging to optimize and significant lab-to-lab variability has been reported. In this study, we evaluated factors that may contr...
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ژورنال
عنوان ژورنال: The Journal of Applied Laboratory Medicine: An AACC Publication
سال: 2017
ISSN: 2475-7241
DOI: 10.1373/jalm.2016.022137